Medical student’s research shows promise as method to help quit smoking
March 19, 2018
The research project of Perisa Ruhi, class of 2018 at the Virginia Tech Carilion School of Medicine, offers new findings to help change smoking behaviors.
Ruhi found that smokers were more likely to value a future without cigarettes when envisioning future events with smoking-related illness symptoms, such as lung cancer. Her study was conducted under the mentorship of Warren Bickel, director of the Addiction Recovery Research Center (ARRC) at the Virginia Tech Carilion Research Institute and professor of psychiatry and behavioral medicine at the school of medicine, and Jeff Stein, research assistant professor at ARRC.
Delay discounting and episodic future thinking
Previous research has found that cigarette smokers discount or devalue future rewards at a higher rate than nonsmokers, a tendency called delay discounting. This behavior may contribute to tobacco dependence because it means smokers are less likely to value the future benefits of not smoking, such as enjoying better health or saving money.
Episodic future thinking (EFT) is one of the most rapidly growing areas of research in cognitive neuroscience and psychology. It involves mental simulation of positive, personally meaningful future events, such as a wedding or graduation. By vividly imagining the event, it becomes less abstract. This concept is becoming more widely incorporated in addiction research interventions, theorizing that if individuals can imagine and appreciate the future, they are less likely to engage in their addiction.
Design and methodology
Using an online crowd sourcing platform, Ruhi recruited and randomly assigned 199 smokers to one of four groups: those who imagined positive future events, those who added symptoms of smoking-related illness to their imagined positive future events, and two control groups for validity.
“Adding the negative component of the smoking-related illnesses was the new part of the research that had never been done before,” Ruhi said. “It essentially changed the participant’s positive event into a negative one.”
All participants completed assessments of three measures: their cigarette craving, how much they were willing to pay for a cigarette (demand), and delay discounting.
The study showed cigarette craving diminished significantly in both groups assigned to imagine the future (with or without experiencing symptoms of smoking-related illness.
“This makes sense,” Ruhi said. “If you’re imagining yourself having lung cancer, you’re probably going to crave cigarettes less.”
Cigarette demand was diminished significantly in the group imagining smoking-related illness in the future, as well in a control group imagining smoking-related illness in the recent past. This suggests that vividly imagining the consequences of smoking shows a therapeutic effect on how people value cigarettes, regardless of when those symptoms are imagined.
“But when we measured delay discounting, things got even more interesting,” Ruhi said.
Ruhi found that participants who envisioned positive future events were less likely to devalue the future. This had been shown in prior studies and was expected, but the more interesting finding was that participants who envisioned themselves with a smoking-related illness (either in the future or in the recent past) showed the opposite effect. It led them to devalue the future more.
“This was truly shocking to me because it was the opposite of my hypothesis,” Ruhi said. “After thinking about it and discussing it with Dr. Stein, it started to make more sense. If you’re imagining yourself with lung cancer, for instance, it may be too stressful to go to a future event, so the future has less value.”
Nonetheless, in comparisons of both smoking-related illness groups (future and recent past), episodic future thinking made participants less likely to devalue the future, suggesting that the episodic future thinking protects against circumstances that increase impulsivity.
Even though Ruhi may not focus on neuroscience or the treatment of addictions in her future career as a general surgeon, she was quick to emphasize their importance to all health care professionals.
“There are so many new discoveries and techniques and treatment options,” she said. “One of the things they’re realizing now is that addictions can relate to things other than drugs or alcohol – food, for example. It’s important for doctors to be aware of this, as it will increase understanding of their patients with addictions.”
Ruhi found her time in the ARRC lab to be an invaluable opportunity as a medical student interested in an academic career.
“Dr. Bickel is an amazing leader and one of the world’s leading addiction and behavioral science researchers, and Dr. Stein provided me with a wealth of knowledge and guidance,” she said. “Overall, it was just an incredible experience.”
The Virginia Tech Carilion School of Medicine is one of only a few medical schools in the country that has such an intensive longitudinal research project requirement as part of its curriculum, a fact that weighed heavily on Ruhi’s decision to come to the school.
“I’ve been able to conduct a research project from the ground up — from coming up with the idea to analyzing the data and everything in between. I’m working on getting it published in an academic journal.”
She even gave a poster presentation about her project at an international conference in Florence, Italy.
“I wouldn’t have gotten these opportunities anywhere else.”
Having received a Letter of Distinction for her project, Ruhi will be one of eight students from the class of 2018 giving oral presentations as part of the VTCSOM Medical Student Research Symposium. In addition, the rest of the class will be giving poster presentations at the event, which will be held during the afternoon of March 23. Read more.